Celebrating a World of SMOC-1 Research

Over 2 decades of research have culminated in several amazing insights into what SMOC-1 is, how it functions at various times in our growth and development, and what some of the consequences may be when it is not functioning properly.

These represent people who have seen SMOC1 in one form or another (people, mice, frogs, worms, chicken) and have published so

All across the world, there are people who care about SMOC1. There are people interested in how it functions in worms,, flies, frogs, mice, and, of course, in humans! We aim to bring this community of scientists together and inspire them to continue their important work and to expand it in ways that can impact those impacted by SMOC1 dysfunction.

We celebrate what has already been done and eagerly await the next insight that can be translated to improved quality of life for our loved ones. If you are a scientist doing research on SMOC-1, help us put you on the map!

Get in touch here.

In January 2025 we had the opportunity to meet with Dr. John Kellum to discuss the emergency situations that seem to arise upon dehydration in children affected by SMOC1 dysfunction. We discussed sepsis, acidosis, and walked through the clinical features of several of these incidents.

In October 2024 we held another Roundtable during which we had an update from Jackson Laboratory and our Science Advisor, Helen walked through these slides.

The SMOC1 Science Roundtable was held in June 2024 and was a tremendous success. We learned from several experts and had a great conversation. See more details here:

Much of our scientific strategy is in appreciation of the master class presented in episode 94 of the amazing Once Upon a Gene podcast. Thank you!!

Click here to see our April 2024 Science & Strategy Update